Journal of Medicinal Chemistry
Volume 41, Issue 13 (June 18, 1998)
Copyright © 1998
American Chemical Society
COMMUNICATIONS TO THE EDITOR | |
2175-2179 | Spiro[1H-indene-1,4'-piperidine] Derivatives As Potent and Selective Non-Peptide Human Somatostatin Receptor Subtype 2 (sst2) Agonists
|
2180-2183 | Isochroman-6-carboxamides as Highly Selective 5-HT1D Agonists: Potential New Treatment for Migraine without Cardiovascular Side Effects
|
EXPEDITED ARTICLES | |
2184-2193 | Inhibition of in Vitro and in Vivo HIV Replication by a Distamycin Analogue That Interferes with Chemokine Receptor Function: A Candidate for Chemotherapeutic and Microbicidal Application
|
2194-2200 | Rational Design and Combinatorial Evaluation of Enzyme Inhibitor Scaffolds: Identification of Novel Inhibitors of Matrix Metalloproteinases
|
2201-2206 | A Pyridoxine Cyclic Phosphate and Its 6-Azoaryl Derivative Selectively Potentiate and Antagonize Activation of P2X1 Receptors
|
ARTICLES | |
2207-2215 | Synthesis and Characterization of Long Chain Alkyl Acyl Carnitine Esters. Potentially Biodegradable Cationic Lipids for Use in Gene Delivery
|
2216-2226 | Molecular Modeling Studies of the DNA-Topoisomerase I Ternary Cleavable Complex with Camptothecin
|
2227-2233 | L-Carnitine Esters as "Soft", Broad-Spectrum Antimicrobial Amphiphiles
|
2234-2242 | N2- and C8-Substituted Oligodeoxynucleotides with Enhanced Thrombin Inhibitory Activity in Vitro and in Vivo
|
2243-2251 | Benzylimidazolines as h5-HT1B/1D Serotonin Receptor Ligands: A Structure-Affinity Investigation
|
2252-2260 | Discovery of a Novel Series of Potent and Selective Substrate-Based Inhibitors of p60c-src Protein Tyrosine Kinase: Conformational and Topographical Constraints in Peptide Design
|
2261-2267 | Three-Dimensional Quantitative Structure-Activity Relationship Study of Nonsteroidal Estrogen Receptor Ligands Using the Comparative Molecular Field Analysis/Cross-Validated r2-Guided Region Selection Approach
|
2268-2277 | 7-Oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridines as Novel Inhibitors of Human Eosinophil Phosphodiesterase
|
2278-2288 | Synthesis and Glutathione S-Transferase Structure-Affinity Relationships of Nonpeptide and Peptidase-Stable Glutathione Analogues
|
2289-2301 | Synthesis and Evaluation of Diphenyl Phosphonate Esters as Inhibitors of the Trypsin-like Granzymes A and K and Mast Cell Tryptase
|
2302-2307 | Studies on Selectin Blockers. 6. Discovery of Homologous Fucose Sugar Unit Necessary for E-Selectin Binding
|
2308-2318 | Synthesis and Antitumor Activity of Ring A- and F-Modified Hexacyclic Camptothecin Analogues
|
2319-2332 | Comprehensive Study on Structure-Activity Relationships of Rifamycins: Discussion of Molecular and Crystal Structure and Spectroscopic and Thermochemical Properties of Rifamycin O
|
2333-2338 | Structure-Activity Requirements for Flavone Cytotoxicity and Binding to Tubulin
|
2339-2344 | Auxiliary Agents for the Peroral Administration of Peptide and Protein Drugs: Synthesis and Evaluation of Novel Pepstatin Analogues
|
2345-2360 | GPIIb/IIIa Integrin Antagonists with the New Conformational Restriction Unit, Trisubstituted -Amino Acid Derivatives, and a Substituted Benzamidine Structure
|
2361-2370 | Synthesis and Quantitative Structure-Activity Relationships of N-(1-Benzylpiperidin-4-yl)phenylacetamides and Related Analogues as Potent and Selective 1 Receptor Ligands
|
2371-2379 | Syntheses and Anticholinesterase Activities of (3aS)-N,N8-Bisnorphenserine, (3aS)-N1,N8-Bisnorphysostigmine, Their Antipodal Isomers, and Other Potential Metabolites of Phenserine
|
2380-2389 | 2-Substituted Analogues of 4'-Iodococaine: Synthesis and Dopamine Transporter Binding Potencies
|
2390-2410 | Inhibitors of Acyl-CoA:Cholesterol O-Acyltransferase. 2. Identification and Structure-Activity Relationships of a Novel Series of N-Alkyl-N-(heteroaryl-substituted benzyl)-N'-arylureas
|
2411-2423 | Nonsymmetric P2/P2' Cyclic Urea HIV Protease Inhibitors. Structure-Activity Relationship, Bioavailability, and Resistance Profile of Monoindazole-Substituted P2 Analogues
|
NOTES | |
2424-2429 | Optimizing the Binding of Fullerene Inhibitors of the HIV-1 Protease through Predicted Increases in Hydrophobic Desolvation
|
2430-2435 | Synthesis and Dopamine Transporter Affinity of the Four Stereoisomers of (±)-2-(Methoxycarbonyl)-7-methyl-3-phenyl-7-azabicyclo[2.2.1]heptane
|
2436-2438 | Antimycobacterial Activity of Substituted Isosteres of Pyridine- and Pyrazinecarboxylic Acids
|